2,4-Dimethoxybenzylamine → 2-Methyl-2H-pyrazole-3-carboxylic Acid 2,4-dimethoxy-benzylamide

HRID 1644094Notes

Reaction equation

HRID 1644094 reaction equation
[CH3:1][N:2]1[C:6]([C:7]([OH:9])=O)=[CH:5][CH:4]=[N:3]1.[CH3:10][O:11][C:12]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:13]=1[CH2:14][NH2:15]>>[CH3:10][O:11][C:12]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][C:13]=1[CH2:14][NH:15][C:7]([C:6]1[N:2]([CH3:1])[N:3]=[CH:4][CH:5]=1)=[O:9]

Participants

3

Reactant 2

HCID 5972502,4-DimethoxybenzylamineHCID 6431581-methyl-1H-pyrazole-5-carboxylic acid

Product 1

HCID 575278002-Methyl-2H-pyrazole-3-carboxylic Acid 2,4-dimethoxy-benzylamide

Procedure

Prepared in a similar manner to example 4 using 2-methyl-2H-pyrazole-3-carboxylic acid and 2,4-dimethoxy-benzylamine. MS (M+H, 276.2).

Sources & evidence

ORD record
ord-0549589e3a334316a72388d35522d23a
Source dataset
uspto-grants-2012_02
Patent number
US08124121B2

Reaction notes

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