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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644098Generated: October 25, 2026

4-Methoxy-3-methylbenzoic Acid → 4-Methoxy-3-methyl-N-(1-pyridin-2-yl-butyl)-benzamide

https://huagongshe.com/reaction/1644098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-3-methylbenzoic AcidHCID 2759583—
Reactant1-(Pyridin-2-yl)butan-1-amineHCID 22767593—
Product4-Methoxy-3-methyl-N-(1-pyridin-2-yl-butyl)-benzamideHCID 57527755—

Reaction Steps

Prepared in a similar manner to example 4 using 4-methoxy-3-methyl-benzoic acid and 1-pyridin-2-yl-butylamine. 1H NMR (500 MHz, CDCl3): δ 0.91-0.92 (t, 3H), 1.25-1.3 (m, 2H, 1.85-1.9 (m, 2H), 3.86 (s, 3H), 5.25-5.3 (m, 1H), 6.80-6.82 (d, 1H), 7.2-7.3 (m, 2H), 7.42-7.44 (d, 1H), 7.6-7.7 (m, 3H), 8.6 (d, 1H). MS (M+H, 299.1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124121B2
Source datasetuspto-grants-2012_02
ORD IDord-cf96d7f432bc42d2b7da490307b4b6af
Source noteuspto-grants-2012_02