Adenine → HCID 136346341, compound

HRID 1644159Notes

Reaction equation

HRID 1644159 reaction equation
[N:1]1[C:9]([NH2:10])=[C:8]2[C:4]([N:5]=[CH:6][NH:7]2)=[N:3][CH:2]=1.[NH:11]1[C:20](=[O:21])[C:19]2[NH:18][CH:17]=[N:16][C:15]=2[N:14]=[C:12]1[NH2:13]>[Au].C(O)C>[N:1]1[C:9]([NH2:10])=[C:8]2[C:4]([N:5]=[CH:6][NH:7]2)=[N:3][CH:2]=1.[NH:11]1[C:20](=[O:21])[C:19]2[NH:18][CH:17]=[N:16][C:15]=2[N:14]=[C:12]1[NH2:13]

Participants

5

Reactant 2

HCID 190AdenineHCID 135398634Guanine

Product 1

HCID 136346341HCID 136346341, compound

Reagents, catalysts & solvents 2

HCID 23985GoldCatalystHCID 702EthanolSolvent

Procedure

For preparing the sample self-assembled monolayers (SAMs) of nucleobases (i.e., thiol derivatives of adenine, guanine, cytosine, and uracil), gold substrates were soaked into 10 mM sample ethanolic solutions (HPLC-grade ethanol, Wako Pure Chemical, Osaka, Japan) for 30 min, 45 min, or 1 h. After being taken out of the solution, the gold substrates were rinsed with ethanol to remove excess sample nucleobases physisorbed on the SAMs, and dried in vacuum. The sample adenine/guanine mixed SAMs were prepared from the aqueous 10 mM mixed solutions of adenine and guanine with their differing molar ratios.

Workup

  1. custom1 h
  2. washthe gold substrates were rinsed with ethanol
  3. customto remove excess sample nucleobases
  4. customdried in vacuum

Sources & evidence

ORD record
ord-e286f2493e554942bca03e3afecd0a00
Source dataset
uspto-grants-2012_02
Patent number
US08124417B2

Reaction notes

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