Ethanol → 1-Propanaminium, N,N-dimethyl-N-propyl-, hydroxide (1:1)

HRID 1644162Notes

Reaction equation

HRID 1644162 reaction equation
CI.[I-].[CH3:4][N+:5]([CH3:12])([CH2:9][CH2:10][CH3:11])[CH2:6][CH2:7][CH3:8].C([OH:15])C>C(NCCC)CC>[OH-:15].[CH3:4][N+:5]([CH3:12])([CH2:9][CH2:10][CH3:11])[CH2:6][CH2:7][CH3:8]

Participants

5

Reactant 3

HCID 702EthanolHCID 6328Methyl iodideHCID 85787840HCID 85787840, compound

Product 1

HCID 220565641-Propanaminium, N,N-dimethyl-N-propyl-, hydroxide (1:1)

Reagents, catalysts & solvents 1

HCID 8902DipropylamineSolvent

Procedure

15 ml of dipropylamine in 50 ml of ethanol as a solvent and with KHCO3 as a buffer are reacted with 20 ml of methyl iodide at a temperature of from 40 to 50° C. in a water bath with stirring. After 2 hours, cooling to room temperature was effected, the product dimethyldipropylammonium iodide crystallizing out. The solid filtrate was washed in ethanol. An aqueous solution of the iodide was converted over an Amberlyst anion exchanger into dimethyldipropylammonium hydroxide.

Workup

  1. washThe solid filtrate was washed in ethanol

Sources & evidence

ORD record
ord-7fe5cdac57654fd894c32943dcd66f99
Source dataset
uspto-grants-2012_02
Patent number
US08124560B2

Reaction notes

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