2-Furancarboxylic acid, hydrazide → HCID 66776522, compound

Participants

Reaction Steps

A mixture of 2a (1.50 g, 11.9 mmol) and (R)-citronellal (2.74 g, 17.7 mmol) in ethanol (30 ml) was heated under reflux for 2 h. After cooling to room temperature, the product was concentrated and the excess of citronellal removed by Kugelrohr distillation (120° C., 0.39 mbar) to give 2.03 g (55%) of a yellow solid as a mixture of two isomers (ca. 7:1).

Provenance & Evidence