HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane → 7-Bromoquinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 7-Bromo-2-chloroquinoline | HCID 14221034 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 7-Bromoquinolin-2(1H)-one | HCID 14221025 | — |
Reaction Steps
7-Bromo-2-chloroquinoline was heated in 5M HCl (100 mL) and dioxane (10 mL) for 1 hour at reflux. The Reaction mixture was cooled, filtered and washed with water to give the title compound, 2.89 g, as a colorless solid, mp 295° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124602B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-980dd5ee7918474ca6094261972c40f9 |
| Source note | uspto-grants-2012_02 |