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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644355Generated: October 30, 2026

1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile → HCID 178509460, compound

https://huagongshe.com/reaction/1644355

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrileHCID 60200920—
ReactantHCID 178453917HCID 178453917—
ProductHCID 178509460HCID 178509460—

Reaction Steps

tert-Butyl{trans-4-[2-(6-cyano-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]cyclohexyl}carbamate (Intermediate 78) was reacted as described for Intermediate 14. The crude trifluoro acetate of the title compound was used without further purification for the next step (quantitative yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124602B2
Source datasetuspto-grants-2012_02
ORD IDord-abedfa6ed0864618b873b313c4510054
Source noteuspto-grants-2012_02