4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine → 1-(3,4,5-Trimethoxy-benzyl)-3-[2-[4-[1-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-4-hydroxy-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenylmethyl)-2-oxo-pyrrolidine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:29])[C:9]([CH2:12][CH2:13][S:14]([CH3:15])(=[O:16])=[O:17])([CH2:18][c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:30][c:31]([O:35][CH3:36])[c:32]1[O:33][CH3:34].[F:37][c:38]1[cH:39][cH:40][c:41]([CH2:42][n:43]2[c:44]([C:52]3([OH:58])[CH2:53][CH2:54][NH:55][CH2:56][CH2:57]3)[n:45][c:46]3[c:47]2[cH:48][cH:49][cH:50][cH:51]3)[cH:59][cH:60]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:29])[C:9]([CH2:12][CH2:13][N:55]3[CH2:54][CH2:53][C:52]([c:44]4[n:43]([CH2:42][c:41]5[cH:40][cH:39][c:38]([F:37])[cH:60][cH:59]5)[c:47]5[c:46]([n:45]4)[cH:51][cH:50][cH:49][cH:48]5)([OH:58])[CH2:57][CH2:56]3)([CH2:18][c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:30][c:31]([O:35][CH3:36])[c:32]1[O:33][CH3:34]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-624f9b096e744c7b99840c659b836442
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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