2,6-Dichloroquinolin-5-amine → N-(2,6-Dichloro-5-quinolinyl)-4-(trifluoromethyl)-cyclohexaneacetamide
Reaction equation
[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:13])[c:8]([NH2:12])[c:9]2[cH:10][cH:11]1.[F:14][C:15]([CH:16]1[CH2:17][CH2:18][CH:19]([CH2:22][C:23](=[O:24])[OH:25])[CH2:20][CH2:21]1)([F:26])[F:27]>>[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:13])[c:8]([NH:12][C:23]([CH2:22][CH:19]3[CH2:18][CH2:17][CH:16]([C:15]([F:14])([F:26])[F:27])[CH2:21][CH2:20]3)=[O:24])[c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-98d0be96838b4659abcb958d9b0dbcf0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…