HCID 6470109, compound → 3-[(2-Thienylsulfonyl)amino]benzoic acid

HRID 1644623Notes

Reaction equation

HRID 1644623 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([NH:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][CH:19]=1)[C:13]([O:15]C)=[O:14])(=[O:8])=[O:7].FC1C=CC=CC=1COC1C=C(C=C([N+]([O-])=O)C=1)C(O)=O>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[S:6]([NH:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][CH:19]=1)[C:13]([OH:15])=[O:14])(=[O:8])=[O:7]

Participants

3

Reactant 2

HCID 6470109HCID 6470109, compoundHCID 66775223HCID 66775223, compound

Product 1

HCID 8000883-[(2-Thienylsulfonyl)amino]benzoic acid

Procedure

Methyl 3-(thiophene-2-sulfonamido)benzoate (242a) was hydrolyzed to the acid in an analogous matter to that described in for the formation of 3-(2-fluorobenzyloxy)-5-nitrobenzoic acid.

Sources & evidence

ORD record
ord-b2b35bdb7cc545a9814bf90dd4969d91
Source dataset
uspto-grants-2012_02
Patent number
US08124617B2

Reaction notes

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