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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 164474Generated: October 30, 2026

Hydrochloric Acid → (3aRS,7aRS)-7,7-bis(2-fluorophenyl)-2-[(2-dimethylaminophenyl)acetyl]perhydro-4-isoindolone

https://huagongshe.com/reaction/164474

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
Reactant7,7-bis(2-fluorophenyl)-2,3,3a,5,6,7a-hexahydro-1H-isoindol-4-oneHCID 9818783—
Reactant2-(2-(Dimethylamino)phenyl)acetic acidHCID 20466109—
Product(3aRS,7aRS)-7,7-bis(2-fluorophenyl)-2-[(2-dimethylaminophenyl)acetyl]perhydro-4-isoindoloneHCID 67916112—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-afdbe0d2ecb346c8a7d8078a12ddde7f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)