Hydrochloric Acid → HCID 71763881, compound

Participants

Reaction Steps

The intermediate from step A (8.6 g, 12.43 mmol) was added to 4 N HCl in dioxane (200 mL) at 0° C. The solution was then stirred at room temperature for 1 h. The volatiles were removed in vacuo. The residue was dissolved in 750 mL ether, washed with 2N sodium hydroxide aqueous, brine and saturated sodium bicarbonate. The organic layer was dried over Na2SO4 and concentrated in vacuo to give a foam solid (8.12 g crude). M++1: 592.49.

Provenance & Evidence