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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1644870Generated: October 31, 2026

HCID 178476501, compound → [3-(4-{1,2-Dimethyl-1-[5-(pyridin-2-ylmethoxy)pyridin-2-yl]propyl}phenyl)-1,2,4-oxadiazol-5-yl]methyl acetate

https://huagongshe.com/reaction/1644870

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178476501HCID 178476501—
SolventO-XyleneHCID 7237—
Product[3-(4-{1,2-Dimethyl-1-[5-(pyridin-2-ylmethoxy)pyridin-2-yl]propyl}phenyl)-1,2,4-oxadiazol-5-yl]methyl acetateHCID 57910807—

Reaction Steps

A stirred solution of 3b (0.896 mmol) in xylene (6.00 mL) was heated to 110° C. for approximately 1 h. After cooling to rt, the reaction mixture was concentrated in vacuo to afford the title compound 3c, which was used without further purification in the subsequent reaction. m/z (ES) 473 (MH)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124628B2
Source datasetuspto-grants-2012_02
ORD IDord-37eed5caad4947ac8d67476c94e0691a
Source noteuspto-grants-2012_02