Cyclopentanethiol → HCID 59152922, compound

Participants

Reaction Steps

Starting with {(R)-4-[(3-fluoro-5-trifluoromethyl-benzenesulfonyl)-methyl-amino]-4,5,6,7-tetrahydro-indazol-1-yl}-acetic acid ethyl ester (1st step intermediate of example 8-1) and cyclopentanethiol using the method analogous to the method analogous to the one described for the 1st step of example 7-1, {(R)-4-[(3-Cyclopentylsulfanyl-5-trifluoromethyl-benzenesulfonyl)-methyl-amino]-4,5,6,7-tetrahydro-indazol-1-yl}-acetic acid ethyl ester (20.2 mg, 83%) was obtained. MS cald. for C24H30F3N3O4S2 545, obsd. (ESI+) [(M+H)+] 546.

Provenance & Evidence