HCID 57917511, compound → HCID 57917493, compound

Participants

Reaction Steps

Using standard Swern oxidation reaction conditions (see step (v)/Example 80 or step (iii)/Example 81), tert-butyl 4-(3-fluorophenyl)-4-(hydroxymethyl)piperidine-1-carboxylate (0.5 g, 1.61 mmol) was oxidized to yield tert-butyl 4-(3-fluorophenyl)-4-formylpiperidine-1-carboxylate which was directly taken through to the next step without further purification.

Provenance & Evidence