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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1645267Generated: October 31, 2026

HCID 59190180, compound → HCID 59190119, compound

https://huagongshe.com/reaction/1645267

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59190180HCID 59190180—
Solvent1,4-Dioxane hydrochlorideHCID 20443148—
ProductHCID 59190119HCID 59190119111.7%

Reaction Steps

A solution of (E)-tert-butyl 3-(5-((2-oxoindolin-3-ylidene)methyl)furan-2-yl)phenylcarbamate (600 mg, 1.49 mmol) in HCl/dioxane (4M, 3.0 mL) was stirred over night. The resulting precipitate was collected by filtration to yield desired (E)-3-((5-(3-aminophenyl)furan-2-yl)methylene)indolin-2-one (503 mg). LCMS (ES): m/z 303 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124649B2
Source datasetuspto-grants-2012_02
ORD IDord-03fe875cd45a451381c151bf30fc5429
Source noteuspto-grants-2012_02