HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 66772746, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 5-Chlorooxindole | HCID 152801 | — |
| Reactant | 5-Formylfuran-2-boronic acid | HCID 2734355 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66772746 | HCID 66772746 | 20.4% |
Reaction Steps
A solution of 5-chlorooxindole (999 mg, 5.98 mmol), 5-formylfuran-2-boronic acid (832 mg, 5.98 mmol) and piperidine (0.59 mL, 5.98 mmol) in EtOH (5.0 mL) was stirred at rt 90 min. The resulting precipitate was collected by filtration to yield the desired compound (354 mg). LCMS (ES): m/z 290 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124649B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-736c14dbee5f4df9b565bb33d7df3295 |
| Source note | uspto-grants-2012_02 |