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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1645363Generated: October 27, 2026

7-Methoxy-3-methyl-1H-indole-2-carboxylic acid → 3-{4-[(7-methoxy-3-methyl-1H-indole-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1645363

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Methoxy-3-methyl-1H-indole-2-carboxylic acidHCID 649614—
Reactant3-(4-Amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl esterHCID 66772790—
Product3-{4-[(7-methoxy-3-methyl-1H-indole-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl esterHCID 46223697—

Reaction Steps

With a procedure similar to the example above, 3-{4-[(7-methoxy-3-methyl-1H-indole-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester was prepared from 7-methoxy-3-methyl-1H-indole-2-carboxylic acid and 3-(4-amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl ester. LCMS calcd for C24H27N3O5 (m/e) 437, obsd 438 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124766B2
Source datasetuspto-grants-2012_02
ORD IDord-603efb7b88064de2ae0cb2d2e96bc286
Source noteuspto-grants-2012_02