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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1645371Generated: November 1, 2026

3-(Methoxymethyl)-1-benzofuran-2-carboxylic acid → 3-{4-[(3-Methoxymethyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1645371

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Methoxymethyl)-1-benzofuran-2-carboxylic acidHCID 2461722—
Reactant3-(4-Amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl esterHCID 66772790—
Product3-{4-[(3-Methoxymethyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl esterHCID 59365182—

Reaction Steps

With a procedure similar to the example above, 3-{4-[(3-methoxymethyl-benzofuran-2-carbonyl)-amino]-phenoxy}-pyrrolidine-1-carboxylic acid ethyl ester was prepared from 3-methoxymethyl-benzofuran-2-carboxylic acid and 3-(4-amino-phenoxy)-pyrrolidine-1-carboxylic acid ethyl ester. LCMS calcd for C24H26N2O6 (m/e) 438, obsd 439 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124766B2
Source datasetuspto-grants-2012_02
ORD IDord-05301dd839be4d0891bb96447bd85d5f
Source noteuspto-grants-2012_02