7-Fluoro-3-methyl-benzofuran-2-carboxylic acid → HCID 59365173, compound

HRID 1645372Notes

Reaction equation

HRID 1645372 reaction equation
[F:1][C:2]1[C:10]2[O:9][C:8]([C:11]([OH:13])=O)=[C:7]([CH3:14])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:15][O:16][CH2:17][CH2:18][N:19]([CH3:27])[C:20]1[CH:25]=[CH:24][C:23]([NH2:26])=[CH:22][N:21]=1>>[CH3:15][O:16][CH2:17][CH2:18][N:19]([CH3:27])[C:20]1[N:21]=[CH:22][C:23]([NH:26][C:11]([C:8]2[O:9][C:10]3[C:2]([F:1])=[CH:3][CH:4]=[CH:5][C:6]=3[C:7]=2[CH3:14])=[O:13])=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 25603137-Fluoro-3-methyl-benzofuran-2-carboxylic acidHCID 52937159N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine

Product 1

HCID 59365173HCID 59365173, compound

Procedure

With a procedure similar to the example above, 7-fluoro-3-methyl-benzofuran-2-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 7-fluoro-3-methyl-benzofuran-2-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C19H20FN3O3 (m/e) 357, obsd 358 (M+H).

Sources & evidence

ORD record
ord-4656f9976f614c1090ac1ea7719fc916
Source dataset
uspto-grants-2012_02
Patent number
US08124766B2

Reaction notes

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