Ammonia → HCID 86653376, compound

Participants

Reaction Steps

5 g (18.2 mmol) of the cis-t-butyl-2-methoxy-3,5-dioxane-7-nitro-heptanoate obtained in Example 1 was added to a mixture solvent of 50 mL of MeOH and 50 mL of THF saturated with ammonia. Hydrogenation was performed for 6 hours at room temperature in the presence of 10% Pd/C catalyst. 4.43 g (88.6%) of the target compound was obtained as colorless oil.

Provenance & Evidence