HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromonaphthalene → HCID 59235720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromonaphthalene | HCID 11372 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | Sodium t-butoxide | HCID 23676156 | — |
| Reactant | HCID 59235714 | HCID 59235714 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 59235720 | HCID 59235720 | 76.3% |
Reaction Steps
4-(4′-Diphenylaminobiphenyl-4-yl)pyrimidine-2-amine (100 mg, 0.24 mmol), 2-bromonaphthalene (54.6 mg, 0.264 mmol), dichlorobis(triphenylphosphine)palladium(II) (17 mg, 0.024 mmol), Xantphos (14 mg, 0.024 mmol) and sodium t-butoxide (35 mg, 0.36 mmol) were added in toluene (3 mL), and refluxed under nitrogen atmosphere for 14 hours. This solution was cooled, and the precipitated solid was washed with cold toluene and water to obtain the title compound (99 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124762B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-3a60adcac7784cc38a7cf7087e7a02bd |
| Source note | uspto-grants-2012_02 |