Triethylamine → HCID 86645891, compound

Participants

Reaction Steps

With cooling with ice, triethylamine (1.51 mL, 10.84 mol) and mesyl chloride (0.643 mL, 8.13 mmol) were added in that order to an ethyl acetate (10 mL) solution of a compound, methyl (1S*,3R*)-3-hydroxycyclohexanecarboxylic acid (857 mg, 5.42 mmol) known in a reference (Tetrahedron, 2003, Vol. 59, pp. 7465-7471), and then stirred at room temperature for 1 hour. The reaction solution was kept under cooling with ice for while, and then the reaction liquid was filtered. The resulting filtrate was concentrated under reduced pressure to give the intended product (1.18 g, 92%).

Provenance & Evidence