HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dioxaspiro[5.5]undec-3-ylmethanol → 2-(((4-(1,5-Dioxaspiro[5.5]undec-3-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dioxaspiro[5.5]undec-3-ylmethanol | HCID 15286693 | — |
| Reactant | 2-(((4-((2-Methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776002 | — |
| Product | 2-(((4-(1,5-Dioxaspiro[5.5]undec-3-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776104 | 8.4% |
Reaction Steps
The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 1,5-dioxaspiro[5.5]undec-3-ylmethanol obtained in the step (25a) to obtain the title compound (125 mg, total yield: 8.4%) as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124780B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-9b177d0027014b83a6a14a1b105cf5af |
| Source note | uspto-grants-2012_02 |