HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxaspiro(4.5)decan-8-ol → 2-(((4-(1,4-Dioxaspiro[4.5]dec-8-yloxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxaspiro(4.5)decan-8-ol | HCID 567352 | — |
| Reactant | 2-(((4-((2-Methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776002 | — |
| Product | 2-(((4-(1,4-Dioxaspiro[4.5]dec-8-yloxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776018 | 7.3% |
Reaction Steps
The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 1,4-dioxaspiro[4.5]decan-8-ol obtained in the step (27a) to obtain the title compound (230 mg, total yield: 7.3%) as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124780B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-3b68b442f1634b169cc49ffeeddc2be6 |
| Source note | uspto-grants-2012_02 |