2-(2,5,5-Trimethyl-1,3-dioxan-2-yl)ethanol → HCID 66775761, compound

HRID 1645590Notes

Reaction equation

HRID 1645590 reaction equation
[Na:1].COC1OCC([CH2:10][O:11][C:12]2[CH:17]=[CH:16][N:15]=[C:14]([CH2:18][S:19]([C:21]3[NH:25][C:24]4[CH:26]=[CH:27][CH:28]=[CH:29][C:23]=4[N:22]=3)=[O:20])[C:13]=2[CH3:30])CO1.[CH3:31][C:32]1([CH2:40]CO)[O:37][CH2:36][C:35]([CH3:39])([CH3:38])[CH2:34][O:33]1>>[Na:1].[CH3:30][C:13]1[C:14]([CH2:18][S:19]([C:21]2[NH:22][C:23]3[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=3[N:25]=2)=[O:20])=[N:15][CH:16]=[CH:17][C:12]=1[O:11][CH2:10][CH2:31][C:32]1([CH3:40])[O:37][CH2:36][C:35]([CH3:39])([CH3:38])[CH2:34][O:33]1

Participants

3

Reactant 2

HCID 232529502-(2,5,5-Trimethyl-1,3-dioxan-2-yl)ethanolHCID 667760022-(((4-((2-Methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt

Product 1

HCID 66775761HCID 66775761, compoundYield 7.2%

Procedure

The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 2-(2,5,5-trimethyl-1,3-dioxan-2-yl)ethanol obtained in the step (34a) to obtain the title compound (196 mg, total yield: 7.2%) as a light yellow solid.

Workup

  1. customobtained in the step (34a)

Sources & evidence

ORD record
ord-98f75ae8a2774ce8b3d16d2dc5ac3496
Source dataset
uspto-grants-2012_02
Patent number
US08124780B2

Reaction notes

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