HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(6-Methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethanol → 2-(((3-Methyl-4-(2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(6-Methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethanol | HCID 59792495 | — |
| Reactant | 2-(((4-((2-Methoxy-1,3-dioxan-5-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776002 | — |
| Product | 2-(((3-Methyl-4-(2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776191 | 5.5% |
Reaction Steps
The same procedure as in the steps (6b) to (6f) of Example 6 was repeated using 2-(6-methyl-5,7-dioxaspiro[2.5]oct-6-yl)ethanol obtained in the step (35a) to obtain the title compound (163 mg, total yield: 5.5%) as a light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124780B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-036b215aa5554e25b196ef5142276879 |
| Source note | uspto-grants-2012_02 |