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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1645613Generated: October 30, 2026

1,1-Dihydroxypropan-2-one → (2-(Fluoromethyl)-1,3-dioxolan-2-yl)methanol

https://huagongshe.com/reaction/1645613

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-Dihydroxypropan-2-oneHCID 13180982—
Reactant(2-(Fluoromethyl)-1,3-dioxan-2-yl)methanolHCID 59792600—
SolventEthylene GlycolHCID 174—
Product(2-(Fluoromethyl)-1,3-dioxolan-2-yl)methanolHCID 5979237913.8%

Reaction Steps

The same procedure as in the steps (44a) to (44c) using dihydroxyacetone except that ethylene glycol was used instead of 1,3-propanediol used in Example 44 to obtain the title compound (543 mg, total yield: 13.8%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08124780B2
Source datasetuspto-grants-2012_02
ORD IDord-2e5bbc16566e474db50cfb637f9b01f0
Source noteuspto-grants-2012_02