HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Benzodioxane-2-methanol → 2-(((4-(2,3-Dihydro-1,4-benzodioxin-2-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Benzodioxane-2-methanol | HCID 19314 | — |
| Reactant | 2-(((3-Methyl-4-(2-(2-propyl-1,3-dioxan-2-yl)ethoxy)pyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776694 | — |
| Product | 2-(((4-(2,3-Dihydro-1,4-benzodioxin-2-ylmethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776275 | 3% |
Reaction Steps
The same procedure as in the steps (8c) to (8g) of Example 8 was repeated using 2-hydroxymethyl-1,4-benzodioxane to obtain the title compound (141 mg, total yield: 3%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08124780B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-cd387b0f5eb24626a0e124c2eeb511ad |
| Source note | uspto-grants-2012_02 |