1,3-Dioxolane-4-methanol → HCID 66776278, compound

HRID 1645658Notes

Reaction equation

HRID 1645658 reaction equation
[Na:1].CC1(C)COC(C[O:10][C:11]2[CH:16]=[CH:15][N:14]=[C:13]([CH2:17][S:18]([C:20]3[NH:24][C:23]4[CH:25]=[CH:26][CH:27]=[CH:28][C:22]=4[N:21]=3)=[O:19])[C:12]=2[CH3:29])OC1.[CH2:31]1[O:35][CH2:34][O:33][CH:32]1[CH2:36]O>>[Na:1].[O:35]1[CH2:31][CH:32]([CH2:36][O:10][C:11]2[CH:16]=[CH:15][N:14]=[C:13]([CH2:17][S:18]([C:20]3[NH:21][C:22]4[CH:28]=[CH:27][CH:26]=[CH:25][C:23]=4[N:24]=3)=[O:19])[C:12]=2[CH3:29])[O:33][CH2:34]1

Participants

3

Reactant 2

HCID 216181,3-Dioxolane-4-methanolHCID 667765882-(((4-((5,5-Dimethyl-1,3-dioxan-2-yl)methoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt

Product 1

HCID 66776278HCID 66776278, compound

Procedure

The same procedure as in the steps (1c) to (1g) of Example 1 was repeated using glycerol formal (1.76 ml, 20.3 mmol) to obtain the title compound (87 mg, 0.22 mmol) as a beige solid.

Sources & evidence

ORD record
ord-da9adfc047df4f5e84c79b05bb37cdfb
Source dataset
uspto-grants-2012_02
Patent number
US08124780B2

Reaction notes

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