Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Benzylphenol | HCID 7563 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6-Chloro-1-hexanol | HCID 74828 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 15006941 | HCID 15006941 | — |
Reaction Steps
A mixture of 40.0 g (0.217 mole) of p-benzylphenol (Eastman) and 29.7 g (0.217 mole) of 6-chlorohexan-1-ol (MCB) in 500 ml of dry dimethylformamide is stirred and heated to about 100° C., after which 33.1 g (0.24 mole) of potassium carbonate is added, and the mixture refluxed for 2.5 hours. The mixture is cooled, poured into ice-water, and 50 ml of 10% NaOH is added. The mixture is extracted with ether, the ether extracts washed with water and brine, dried (Mg2SO4), and the ether evaporated. The resultant oil is redistilled to give the product as a water-white oil fraction distilling at 140-175° C., 0.05 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05177108 |
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| Source dataset | uspto-grants-1993_01 |
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| ORD ID | ord-2c956414b9fd49caaa8b03e4591aadc7 |
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| Source note | uspto-grants-1993_01 |
|---|
