反应详情

A mixture of 10.0 g (62.0 mmol) of 1,5-dihydroxyisoquinoline in 500 ml of HOAc and 2 g of 20% Pd-C was hydrogenated at room temperature until the required amount of hydrogen was absorbed. The solution was filtered and concentrated. The resulting solid was recrystallized from water (200 ml) to give 8.74 g (86%) of product; mp 195°-198°.

1. customwas hydrogenated at room temperature
2. customwas absorbed
3. filtrationThe solution was filtered
4. concentrationconcentrated
5. customThe resulting solid was recrystallized from water (200 ml)