N-Methyl-L-Alanine → HCID 19100939, compound

HRID 1645989Notes

Reaction equation

HRID 1645989 reaction equation
[CH2:1]([N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].[CH3:13][NH:14][C@H:15](C(O)=O)[CH3:16]>C1(C)C=CC=CC=1>[CH3:13][N:14]1[CH:15]([CH3:16])[CH2:3][CH:2]2[CH:11]1[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:1]2

Participants

4

Reactant 2

HCID 5288725N-Methyl-L-AlanineHCID 11084330Ethyl allyl(2-oxoethyl)carbamate

Product 1

HCID 19100939HCID 19100939, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

17.2 g (0.1 mol) of ethyl N-allyl-N-(2-oxoethyl)-carbamate are heated under reflux overnight with 10.5 g (0.1 mol) of N-methylalanine in 300 ml of toluene. The mixture is concentrated and the residue is distilled.

Workup

  1. concentrationThe mixture is concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-fd37b9369130454a89c7d854fceb25fc
Source dataset
uspto-grants-1993_01
Patent number
US05177210

Reaction notes

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