HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Proline → Ethyl 1,4-diazatricyclo[6.3.0.02,6]undecane-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Proline | HCID 145742 | — |
| Reactant | Ethyl allyl(2-oxoethyl)carbamate | HCID 11084330 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Ethyl 1,4-diazatricyclo[6.3.0.02,6]undecane-4-carboxylate | HCID 53870311 | — |
Reaction Steps
8.6 g (50 mmol) of ethyl N-allyl-N-(2-oxoethyl)-carbamate are heated under reflux overnight with 5.8 g (50 mmol) of proline in 200 ml of toluene. The mixture is concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05177210 |
| Source dataset | uspto-grants-1993_01 |
| ORD ID | ord-49aae351d151408d8d0a9439d1d2dab0 |
| Source note | uspto-grants-1993_01 |