Formic Acid → HCID 19738527, compound

HRID 1646030Notes

Reaction equation

HRID 1646030 reaction equation
C[O:2][CH:3](OC)[CH2:4][N:5]([CH2:11][C:12]([F:14])=[CH2:13])[C:6](=[O:10])[O:7][CH2:8][CH3:9].C(O)=O.[Cl-].[Na+]>O>[F:14][C:12](=[CH2:13])[CH2:11][N:5]([CH2:4][CH:3]=[O:2])[C:6](=[O:10])[O:7][CH2:8][CH3:9]

Participants

5

Reactant 3

HCID 284Formic AcidHCID 5234Sodium ChlorideHCID 19738534HCID 19738534, compound

Product 1

HCID 19738527HCID 19738527, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

14.1 g (60 mmol) of ethyl N-(2,2-dimethoxyethyl)-N-(2-fluoroallyl)-carbamate are heated under reflux for three hours with 6.3 ml of formic acid in 120 ml of water. The solution is saturated with sodium chloride and extracted several times with methylene chloride, the organic solutions are washed with saturated sodium hydrogen carbonate solution, dried over magnesium sulphate and concentrated, and the residue is distilled.

Workup

  1. extractionextracted several times with methylene chloride
  2. washthe organic solutions are washed with saturated sodium hydrogen carbonate solution
  3. dry with materialdried over magnesium sulphate
  4. concentrationconcentrated
  5. distillationthe residue is distilled

Sources & evidence

ORD record
ord-9c9a99147f4547a6994495fdbf7a6145
Source dataset
uspto-grants-1993_01
Patent number
US05177210

Reaction notes

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