3-Phenylprop-2-Enal → HCID 54323214, compound

Participants

Reaction Steps

4.0 g of a 15% strength by weight potassium hydroxide solution were added dropwise to a solution of 26.4 g of cinnamaldehyde and 26.0 g of 2-acetyl-2-methyl -1,3-dioxolan in 100 ml of methanol in the course of 10 minutes at from 20° to 25° C., and the mixture was stirred for a further 4 hours at from 20° to 25° C. Thereafter, the solvent was distilled off, the residue was taken up in 200 ml of tert-butyl methyl ether and the solution was washed with water and dried over sodium sulfate After the solvent had been distilled off, the crude product was distilled at from 150° to 155° C. and at 0.04 mbar.

Provenance & Evidence