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HRID1646132

反应详情

EQUATION

反应方程式

HRID 1646132 的结构方程式

REACTANTS

反应物

2
结构：O=C1CCC(=O)N1Br
HCID67184

1-Bromopyrrolidine-2,5-dione

C4H4BrNO2

结构：CCCCc1ncc(C=O)n1Cc1ccccc1Cl
HCID10107530

1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]-

C15H17ClN2O

PRODUCTS

生成物

1
结构：CCCC(Br)c1ncc[nH]1
HCID19936731

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)(Cl)Cl
溶剂HCID5943

Carbon tetrachloride

CCl4

PROCEDURE

实验过程

A mixture of 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde and N-bromosuccinimide in carbon tetrachloride is irradiated to give the 2-(1 bromobutyl)imidazole which is dehydrobrominated by treating 1,8-diazabicyclo[4.5.0]undec-1-ene in tetrahydrofuran to give 2-(1-butenyl)-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde.

WORKUP

后处理

  1. customis irradiated