HCID 178441740, compound → HCID 178441739, compound

HRID 1646133Notes

Reaction equation

HRID 1646133 reaction equation
[CH2:1]([C:5]1[N:6]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=2[Cl:32])[C:7](/[CH:12]=[C:13](/[C:20]2[NH:24][N:23]=[N:22][N:21]=2)\[CH2:14][C:15]2[S:16][CH:17]=[CH:18][CH:19]=2)=[C:8]([CH2:10][OH:11])[N:9]=1)[CH2:2][CH2:3][CH3:4]>[O-2].[O-2].[Mn+4]>[CH2:1]([C:5]1[N:6]([CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=2[Cl:32])[C:7](/[CH:12]=[C:13](/[C:20]2[NH:24][N:23]=[N:22][N:21]=2)\[CH2:14][C:15]2[S:16][CH:17]=[CH:18][CH:19]=2)=[C:8]([CH:10]=[O:11])[N:9]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 178441740HCID 178441740, compound

Product 1

HCID 178441739HCID 178441739, compound

Reagents, catalysts & solvents 1

HCID 178418406HCID 178418406, compoundCatalyst

Procedure

The title compound is prepared by manganese dioxide oxidation of the 4-hydroxymethyl-group of (E)-1-[2-n-butyl-1-{(2-chlorophenyl)methyl}-4-hydroxymethyl-1H-imidazol-5-yl]-2-(1H-tetrazol-5-yl]-3-(2-thienyl)-1-propene, prepared in Example 18.

Workup

  1. customprepared in Example 18

Sources & evidence

ORD record
ord-a13d1ef23bd84a2b9f379886d8102cf4
Source dataset
uspto-grants-1993_01
Patent number
US05177096

Reaction notes

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