HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 2-(1 Bromobutyl)imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 1H-Imidazole-5-carboxaldehyde, 2-butyl-1-[(2-chlorophenyl)methyl]- | HCID 10107530 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 2-(1 Bromobutyl)imidazole | HCID 19936731 | — |
Reaction Steps
A mixture of 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde and N-bromosuccinimide in carbon tetrachloride was irradiated to give the 2-(1-bromobutyl)imidazole which was dehydrobrominated by treating 1,8-diazabicyclo[4.5.0]undec-1-ene in tetrahydrofuran to give 2-(1-butenyl)-1-(2-chlorophenyl)-methyl-1H-imidazol-5-carboxyaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05177096 |
| Source dataset | uspto-grants-1993_01 |
| ORD ID | ord-30eeaf66859c4b688fa62c7a2ad75172 |
| Source note | uspto-grants-1993_01 |