HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-N-methylcarbostyril → 1-methyl-3-dimethylaminomethylene-(1H)-quinolin-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-N-methylcarbostyril | HCID 54686436 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 1-methyl-3-dimethylaminomethylene-(1H)-quinolin-2,4-dione | HCID 53654100 | — |
Reaction Steps
A suspension of 1-methyl-4-hydroxy-2(1H)-quinolinone (1.0 gm) in dimethyl formamide dimethyl acetal (5 ml) and methylene chloride (2.0 ml) was refluxed for 1 hour. The resulting dark orange solution was evaporated under reduced pressure to afford 1-methyl-3-dimethylaminomethylene-(1H)-quinolin-2,4-dione. MS: m/e 230 (M+). ##STR37##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05179093 |
| Source dataset | uspto-grants-1993_01 |
| ORD ID | ord-e8d5418d5c764c8793899602fc149752 |
| Source note | uspto-grants-1993_01 |