Phenethyl bromide → HCID 10315211, compound

Participants

Reaction Steps

To a solution of 11-amino-4,5-dihydro-1H-pyrazolo[3,4-a]acridine (4.36 g) in dry DMF (130 ml) was slowly added 922 mg of NaH (60%). The reaction was stirred at room temperature for one hour, then (2-bromoethyl)benzene (3.23 ml) was added and the reaction stirred for four hours. An additional 230 mg of NaH (60%) was added, and then the reaction was stirred for a half hour, after which 0.8 ml of (2-bromoethyl)benzene was added and the reaction was stirred at room temperature overnight.

Provenance & Evidence