Methylhydrazine → HCID 10444799, compound

Participants

Reaction Steps

3,4-Dihydro-2-[(dimethylamino)methylene]-9-[[(dimethylamino)methylene]amino]acridin-1-(2H)-one (3.0 g) was refluxed for 60 min in 150 mL of EtOH containing 8.0 g of methylhydrazine. At the end of this time the solvent was evaporated under reduced pressure and then the residue was adhered to silica with MeOH. Purification by flash chromatography (toluene:MeOH:Et3N, 19:1:1) gave 1.71 g of material which was pure to TLC. This was combined with the product of another run of smaller size and recrystallized from toluene to give analytically pure product, mp 240° (d).

Provenance & Evidence