Water → HCID 53729649, compound

Participants

Reaction Steps

Under a current of argon, a solution of 300 mg of 5-[3-(4-chlorophenylthio)-1-propenyl]-2-methoxymethoxy nitrobenzene in 6 ml of methylene chloride and 283 mg of m-chloroperbenzoic acid added thereto as kept cooled with ice were stirred for eight hours. The reaction mixture was combined with water and extracted from ethyl acetate. The consequently separated organic layer was washed sequentially with a saturated aqueous sodium hydrogen carbonate solution and saturated saline solution in the order mentioned and then dried with anhydrous sodium sulfate. The residue from drying was concentrated under a vacuum and the concentrate was subjected to silica gel column chromatography. From the hexane-ethyl acetate (2:1 V/V) eluate, 240 mg of 5-[3-(4-chlorophenylsulfonyl)-1-propenyl]-2-methoxymethoxy nitrobenzene was obtained in the form of yellow crystals. The yield was 74%.

Provenance & Evidence