Benzyl 3-(2-amino-6-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-amino}pyrimidin-4-yl)piperidine-1-carboxylate → HCID 58733356, compound

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Reaction Steps

At room temperature, 1.36 g (2.46 mmol) of benzyl 3-(2-amino-6-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]amino}pyrimidin-4-yl)piperidine-1-carboxylate (from example LXXIV) and 0.4 g of 10% palladium-on-carbon in ethanol are stirred under an atmosphere of hydrogen for 24 hours. The suspension is filtered off with suction through Celite®, and the filtrate is concentrated.

Provenance & Evidence