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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1646354Generated: November 2, 2026

Butyl chloroformate → Methyl 4-[6-(butoxycarbonyl)aminobenzimidazol-1-ylmethyl]-3-methoxybenzoate

https://huagongshe.com/reaction/1646354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl chloroformateHCID 61140—
ReactantMethyl 4-(6-aminobenzimidazol-1-ylmethyl)-3-methoxybenzoateHCID 14763098—
ProductMethyl 4-[6-(butoxycarbonyl)aminobenzimidazol-1-ylmethyl]-3-methoxybenzoateHCID 2336584734%

Reaction Steps

Using a similar procedure to that described in Example 35, but using butyl chloroformate and (J), the title compound was obtained as a solid in 34% yield; partial NMR: 0.9 (t,3 H, CH3CH2), 1.4 (m,2 H, CH3CH2), 1.6 (m,2 H, CH2CH2O), 4.1 (t,2 H, CH2O).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05179112
Source datasetuspto-grants-1993_01
ORD IDord-a2b76f9a9c6d4e20b4ffdc0c7d3e7245
Source noteuspto-grants-1993_01