Aniline → 1,2,3,4-Tetrahydrocarbazole

HRID 1646405Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1(=O)[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>>[CH2:10]1[C:9]2[NH:1][C:2]3[C:7](=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:8]=2[CH2:13][CH2:12][CH2:11]1

Participants

Reactant 2

HCID 6115Aniline

HCID 7967Cyclohexanone

Product 1

HCID 136641,2,3,4-TetrahydrocarbazoleYield 87%

Procedure

Aniline was reacted with cyclohexanone in the same way as in Example 3. Tetrahydrocarbazole was formed in a yield of 87% of the theoretical yield.

Sources & evidence

ORD record: ord-bcb663bf6d44472aad6c1506f0936c16
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05179211

Reaction notes

Loading…