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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1646407Generated: October 31, 2026

4-Chloroaniline → 3H-Indole, 5-chloro-2,3,3-trimethyl-

https://huagongshe.com/reaction/1646407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3-Methyl-2-butanoneHCID 11251—
Product3H-Indole, 5-chloro-2,3,3-trimethyl-HCID 11769486%

Reaction Steps

p-Chloroaniline was reacted with methyl isopropyl ketone in the same way as in Example 3. 2,3,3-Trimethyl-5-chloro-3-H-indole was formed in a yield of 86% of the theoretical yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05179211
Source datasetuspto-grants-1993_01
ORD IDord-5ab9ed8d82564f03b4ded853efeaced8
Source noteuspto-grants-1993_01