Acetaminophen → N-[4-({3-[[4-Cyano-3-(trifluoromethyl)phenyl](2,2,2-trifluoroethyl)amino]propyl}oxy)phenyl]acetamide
Reaction equation
[C:23]([CH3:24])(=[O:25])[NH:26][c:27]1[cH:28][cH:29][c:30]([OH:33])[cH:31][cH:32]1.[OH:1][CH2:2][CH2:3][CH2:4][N:5]([c:6]1[cH:7][c:8]([C:14]([F:15])([F:16])[F:17])[c:9]([C:10]#[N:11])[cH:12][cH:13]1)[CH2:18][C:19]([F:20])([F:21])[F:22]>>[O:1]([CH2:2][CH2:3][CH2:4][N:5]([c:6]1[cH:7][c:8]([C:14]([F:15])([F:16])[F:17])[c:9]([C:10]#[N:11])[cH:12][cH:13]1)[CH2:18][C:19]([F:20])([F:21])[F:22])[c:30]1[cH:29][cH:28][c:27]([NH:26][C:23]([CH3:24])=[O:25])[cH:32][cH:31]1Participants
3
Sources & evidence
- ORD record
- ord-163dd48513544d599b7eadbc101ec53c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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