Phenylhydrazine → 1H-Indole, 3-butyl-2-methyl-

Participants

Reaction Conditions

Reaction Steps

27 g (0.25 mol) of phenylhydrazine were initially introduced at 90° C. in a solution of 1.12 mol of sodium hydrogen sulphate in 420 ml of water. 30 g (0.263 mol) of heptan-2-one were metered in in the course of 30 min. This mixture was stirred for 7 h at 100° C. After cooling, the batch was neutralised and the organic phase was separated off and distilled. 2-Methyl-3-butylindole was obtained in a yield of 62%.

Provenance & Evidence