Diethylamine → N,N-Diethyl-3,4-methylenedioxybenzamide

Participants

Reaction Steps

A solution of diethylamine (56.2 mL, 0.543 mol) in tetrahydrofuran is added dropwise to a solution of piperonyl chloride (33.4 g, 0.181 mol) in tetrahydrofuran at 0° C. The reaction mixture is stirred for 10 minutes and filtered through diatomaceous earth. The filtrate is concentrated in vacuo to give a solid residue which is recrystalized from ether to afford the title product, 36.7 g (91.8%).

Provenance & Evidence